IMCSzyme® is a genetically modified beta-glucuronidase used to detect a wide range of drugs by hydrolyzing glucuronides in biological fluids. After rapid hydrolysis with IMCSzyme, samples can be analyzed by immunoassay, mass spectrometry, and high-performance liquid chromatography. IMCSzyme hydrolyzes multiple drug classes with higher efficiency as compared to other available enzymes.
CONSISTENT, STABLE, AND PURE ENZYMES
Made in the USA and used to hydrolyze more than one million samples each month. IMCSzyme is the first genetically modified pure beta-glucuronidase. Our pure enzyme hydrolyzes multiple drug classes quickly and with high efficiency. We have an extensive quality control program and manufacturing process that ensures consistency across lots. IMCSzyme is shipped overnight and stored at 2 - 8°C.
CLINICAL TOXICOLOGY: Our enzyme has proven to increase the percentage of drugs hydrolyzed, therefore increasing the accuracy of test results. In addition, IMCSzyme decreases incubation time, enabling same-day test results.
PAIN CARE: Fast comprehensive hydrolysis is critical to maintaining an efficient workflow in testing for pain care drugs.
FORENSIC TOXICOLOGY: Crime labs have discovered using IMCSzyme for hydrolysis in blood, urine, or tissue increases the detection of codeine and other hard to hydrolyze analytes. Our pure enzyme does not contain contaminants that lead to the conversion of 6-monoacetylmorphine (6-MAM) to morphine, among other conversions.
IMCSzyme has been featured in poster presentations at AAC, MSACL, SOFT, AAFS, ASMS, and published in the Journal of Analytical Toxicology.
- Clean, fast, and comprehensive hydrolysis in less than 30 minutes
- Reduce matrix effects - fewer interferents
- Decrease the preparation times and increase throughput
View our additional IMCSzyme studies and resources here.
IMCSzyme® Product Specifications
IMCSzyme® E1F [DOWNLOAD]
Physical Description: | Clear aqueous solution |
Specific Activity (units*/mL): | >50,000 |
Guaranteed Shelf Life: | 12 months |
Storage Temperature: | 2-8°C |
RAPID HYDROLYSIS BUFFER INCLUDED IN EVERY ORDER
The use of our complimentary Rapid Hydrolysis Buffer ensures proper pH for optimal hydrolysis conditions with IMCSzyme.
Frequently Asked Questions
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