OVERVIEW
We offer five desalting resins for small peptide to large biomolecule desalting and enrichment. These resins are often used to bind peptides, nucleotides, and proteins in high-aqueous solutions containing ion suppressing salts and buffers. After binding peptides to the reverse phase resin, the salts and buffers are washed off and the peptides are eluted using a high organic solution, such as methanol or acetonitrile.
BENEFITS
- Consistent, high recoveries resulting in less than 10 percent variance across 96 samples
- Fully automated process with little or no manual intervention
- Templated workflows that combine complex methods
- Delivered with Hamilton Microlab STAR ™ pre-programmed software scripts with an intuitive user interface to control sample volumes, aspirate/dispense cycles, and wash steps
Our pipette tips support desalting applications using these Reverse Phase resins:
- RP
- Large Pore C4
- Silica C8
- Silica C18
- OligoR
View and download our product sheets below:
Before After
Before and after desalting of peptides (from tryptic digested proteins) on MALDI-TOF by IMCStips (a) and (b) were before and after extracted of tryptic Human albumin by IMCStips, (c) and (d) were before and after extracted of tryptic Human α-acid-glycoprotein by IMCStips, (e) and (f) were before and after extracted of tryptic Human pre-albumin by IMCStips.
