IMCS

Integrated Micro-Chromatography Systems, Inc (IMCS) is a biotechnology company focused on delivering tools and services to...

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LATEST NEWS

Comparison of different anion exchange resins in IMCStips to assess binding capacities

This study examines the binding capacities of four anion exchange (AEX) resins in IMCStips using a Hamilton Microlab STAR automated liquid handler. AEX resins are key in purifying biomolecules by binding negatively charged molecules like proteins and nucleic acids. We compare their binding efficiency with bovine serum albumin (BSA) across different pipetting cycles, providing insights into resin selection for optimized purification.

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SizeX750 and SizeX1000 IMCStips® for desalting and buffer exchange on the Dynamic Devices platform

The expansion of IMCStips® SizeX750 and SizeX1000 on the Dynamic Devices platform offers users a simple, fast, and high-throughput solution for removing small molecules like salts, reducing agents, dyes, and buffer molecules. This enhanced product line provides improved purification capabilities, allowing users to scale up their processes beyond the limits of the SizeX100 and SizeX150 IMCStips®. With these advanced options, users can achieve more efficient...

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Plasmid Purification using 5 mL MidiPure™ IMCStips® on the Dynamic Devices Lynx

Plasmid DNA (pDNA) purification is a vital process in molecular biology, genetic engineering, and biotechnology. Traditional mid-scale purification methods, like vacuum manifolds or centrifuge columns, can be slow and limited in throughput. MidiPure™ IMCStips® on the Dynamic Devices platform streamlines pDNA purification in high-throughput environments with...

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In-well hydrolysis at room temperature with IMCSzyme® RT and β-Gone™ Plus

Learn how you could save time with in-well hydrolysis of urine at room temperature for drug testing with the help of IMCSzyme® RT and β-Gone™ Plus β-Glucuronidase Removal Plates (Phenomenex). This in-well hydrolysis method allows you to: Save significant time by conducting hydrolysis directly in the well at room temperature, utilizing IMCSzyme® RT alongside β-Gone™ …

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South Carolina-based IMCS, Tymora Analytical Strengthen Partnership to Streamline Exosome Research

Exosomes gaining attention in biomedical research for potential as diagnostic and therapeutic tools IRMO, S.C. – August 9, 2023 — South Carolina’s Integrated Micro-Chromatography Systems, Inc. (IMCS), a leader in automating laboratory workflows, and Tymora Analytical, an authority in exosome purification and proteomics services, have announced a significant enhancement to their ongoing collaboration to advance …

Read moreSouth Carolina-based IMCS, Tymora Analytical Strengthen Partnership to Streamline Exosome Research

Journal Article: Incorporation of Automated Buffer Exchange Empowers High-Throughput Protein and Plasmid Purification for Downstream Uses

Our latest publication in SLAS Technology highlights IMCS’s successful incorporation of automated buffer exchange into two fully automated workflows: affinity purification and anion exchange. By using pipet-based dispersive solid-phase extraction (dSPE), these workflows are highly adaptable and can address production constraints for biotherapeutics. The inclusion of buffer exchange as a last step in both workflows enables further integration for downstream processing, saving valuable time and increasing efficiency. These findings demonstrate the benefits of incorporating IMCStips into high-throughput protein and plasmid purification, paving the way for a more streamlined and effective biotherapeutics discovery process.

Read moreJournal Article: Incorporation of Automated Buffer Exchange Empowers High-Throughput Protein and Plasmid Purification for Downstream Uses