Journal Article: Incorporation of Automated Buffer Exchange Empowers High-Throughput Protein and Plasmid Purification for Downstream Uses
Our latest publication in SLAS Technology highlights IMCS’s successful incorporation of automated buffer exchange into two fully automated workflows: affinity purification and anion exchange. By using pipet-based dispersive solid-phase extraction (dSPE), these workflows are highly adaptable and can address production constraints for biotherapeutics. The inclusion of buffer exchange as a last step in both workflows enables further integration for downstream processing, saving valuable time and increasing efficiency. These findings demonstrate the benefits of incorporating IMCStips into high-throughput protein and plasmid purification, paving the way for a more streamlined and effective biotherapeutics discovery process.